Pancreatic cancer is a kind of gastrointestinal malignancy with high degree of malignancy, which is difficult to diagnose and treat. Its morbidity and mortality have increased significantly in recent years. 5-year survival rate <1%, is one of the worst prognosis of malignant tumors. Early diagnosis rate of pancreatic cancer is not high, surgical mortality is high, and the cure rate is very low. The incidence of this disease is higher in males than in females, with a ratio of 1.5 ~ 2:1. Male patients are far more common than premenopausal women, and the incidence of postmenopausal women is similar to that of males.
The cause of pancreatic cancer is unclear. It is related to smoking, drinking, high fat and protein diet, excessive coffee consumption, environmental pollution and genetic factors. In recent years, the investigation report found that the incidence of pancreatic cancer in diabetes patients was significantly higher than that in the general population. It has also been noted that there is a certain relationship between the incidence of pancreatic cancer and chronic pancreatitis, and that the proportion of pancreatic cancer in patients with chronic pancreatitis is significantly increased. In addition, there are many factors related to the occurrence of the disease, such as occupation, environment, geography and so on.